Dosage Forms:

Capsule and tablet 200mg and 400mg (discontinued)

Powder for oral suspension 100mg/5ml

Drug Class:

Beta-lactam antibiotics, third-generation oral cephalosporins

Mechanism of Action:

Inhibition of bacterial cell wall mucopeptide synthesis

Indications:

Treatment of a wide range of bacterial infectious diseases such as respiratory infections, treatment of skin and soft tissue infections, treatment of bone or joint infections, treatment of urinary infections, to prevent infection in individuals undergoing surgery.

Dose and Administration:

Adults (over 12 years): 200 milligrams every 12 hours or 400 milligrams once daily

Children 6 months to 12 years: 8 milligrams per kilogram of body weight once daily or 4 milligrams per kilogram of body weight every 12 hours up to a maximum of 400 milligrams per day

Contraindications:

Allergy to any type of antibiotic including penicillins or cephalosporins, in case of alcohol consumption, in case of non-steroidal anti-inflammatory drug use (such as ibuprofen and aspirin), in case of anticoagulant and blood thinner use such as warfarin, in case of bleeding disorders (such as peptic ulcer, hemophilia, and thrombocytopenia), colitis (inflammation of the large intestine), or kidney or liver diseases

Side Effects:

Unusual bruising or bleeding, joint pain, diarrhea, abdominal pain, nausea and vomiting, oral or tongue ulcers, itching or vaginal discharge, appearance of white patches in the mouth or on the tongue

Drug Interactions:

Increases carbamazepine blood concentration. Concurrent use with warfarin increases prothrombin time.

Interactions with laboratory tests: May lead to false positive results in blood glucose tests (does not affect enzymatic methods). May lead to false positives in ketonuria and direct Coombs tests.

Use in Pregnancy and Lactation:

Pregnancy category B, therefore its use is permitted at the physician's discretion. This medication can be used during breastfeeding if deemed appropriate by a physician.

Packaging:

Tablet: one blister of 10 pieces along with a leaflet in a box

Capsule: one blister of 10 pieces along with a leaflet in a box

Powder for preparing 100 milliliters of oral suspension along with a leaflet and dosing spoon in a box

Powder for preparing 50 milliliters of oral suspension along with a leaflet and dosing spoon in a box

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